Non-communicable diseases are severe world health problems mainly in sab Saharan- African countries developing countries including Ethiopia. Cardiovascular diseases are one of the major non-communicable diseases increase with rises of hypertension. Hypertension is elevation of systolic blood pressure greater than or equal to 140 mm Hg and/or diastolic blood pressure greater than or equal to 90 mm Hg. A billion people affected globally and millions of them deaths annually. It is significant risk factor for cardiovascular disorders. Some medicinal plants are traditionally used for treatments hypertension. Psidium guava is one popular medicinal plant which is widely used in traditional medicine treatment of different diseases such as diabetes, vomiting, diarrhea and dyslipidemia. The study was designed to identify the effect of P. guava leaf extract on hypertension in guinea pigs. The study was conducted on eight male guinea pigs to measure the effect of ethanol P. guava leaf extract by using invasive methods. The result was analyzed by using independent student t test and one way ANOVA. Ethanol extract of P. guava leaf showed a significant (p=0.05, p=0.001) reduction of blood pressure of in normotensive guinea pigs in dose dependent manner. The effect of P. guava leaf extract in reduction of blood pressure is may be due to a number of phytochemical contents.
| Published in | American Journal of Biomedical and Life Sciences (Volume 5, Issue 3) |
| DOI | 10.11648/j.ajbls.20170503.12 |
| Page(s) | 47-53 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Blood Pressure, Cardiovascular Diseases, Extract, Effect, Guinea Pigs, Hypertension, Normotensive, Psidium guava
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APA Style
Abayneh Elias, Daniel Seifu, Frank Ashall, Tesfaye Tolessa. (2017). The Effect of Ethanol Psidium guava Leaf Extract on Blood Pressure in Normotensive Guinea Pigs. American Journal of Biomedical and Life Sciences, 5(3), 47-53. https://doi.org/10.11648/j.ajbls.20170503.12
ACS Style
Abayneh Elias; Daniel Seifu; Frank Ashall; Tesfaye Tolessa. The Effect of Ethanol Psidium guava Leaf Extract on Blood Pressure in Normotensive Guinea Pigs. Am. J. Biomed. Life Sci. 2017, 5(3), 47-53. doi: 10.11648/j.ajbls.20170503.12
AMA Style
Abayneh Elias, Daniel Seifu, Frank Ashall, Tesfaye Tolessa. The Effect of Ethanol Psidium guava Leaf Extract on Blood Pressure in Normotensive Guinea Pigs. Am J Biomed Life Sci. 2017;5(3):47-53. doi: 10.11648/j.ajbls.20170503.12
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Download@article{10.11648/j.ajbls.20170503.12,
author = {Abayneh Elias and Daniel Seifu and Frank Ashall and Tesfaye Tolessa},
title = {The Effect of Ethanol Psidium guava Leaf Extract on Blood Pressure in Normotensive Guinea Pigs},
journal = {American Journal of Biomedical and Life Sciences},
volume = {5},
number = {3},
pages = {47-53},
doi = {10.11648/j.ajbls.20170503.12},
url = {https://doi.org/10.11648/j.ajbls.20170503.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20170503.12},
abstract = {Non-communicable diseases are severe world health problems mainly in sab Saharan- African countries developing countries including Ethiopia. Cardiovascular diseases are one of the major non-communicable diseases increase with rises of hypertension. Hypertension is elevation of systolic blood pressure greater than or equal to 140 mm Hg and/or diastolic blood pressure greater than or equal to 90 mm Hg. A billion people affected globally and millions of them deaths annually. It is significant risk factor for cardiovascular disorders. Some medicinal plants are traditionally used for treatments hypertension. Psidium guava is one popular medicinal plant which is widely used in traditional medicine treatment of different diseases such as diabetes, vomiting, diarrhea and dyslipidemia. The study was designed to identify the effect of P. guava leaf extract on hypertension in guinea pigs. The study was conducted on eight male guinea pigs to measure the effect of ethanol P. guava leaf extract by using invasive methods. The result was analyzed by using independent student t test and one way ANOVA. Ethanol extract of P. guava leaf showed a significant (p=0.05, p=0.001) reduction of blood pressure of in normotensive guinea pigs in dose dependent manner. The effect of P. guava leaf extract in reduction of blood pressure is may be due to a number of phytochemical contents.},
year = {2017}
}
TY - JOUR T1 - The Effect of Ethanol Psidium guava Leaf Extract on Blood Pressure in Normotensive Guinea Pigs AU - Abayneh Elias AU - Daniel Seifu AU - Frank Ashall AU - Tesfaye Tolessa Y1 - 2017/06/20 PY - 2017 N1 - https://doi.org/10.11648/j.ajbls.20170503.12 DO - 10.11648/j.ajbls.20170503.12 T2 - American Journal of Biomedical and Life Sciences JF - American Journal of Biomedical and Life Sciences JO - American Journal of Biomedical and Life Sciences SP - 47 EP - 53 PB - Science Publishing Group SN - 2330-880X UR - https://doi.org/10.11648/j.ajbls.20170503.12 AB - Non-communicable diseases are severe world health problems mainly in sab Saharan- African countries developing countries including Ethiopia. Cardiovascular diseases are one of the major non-communicable diseases increase with rises of hypertension. Hypertension is elevation of systolic blood pressure greater than or equal to 140 mm Hg and/or diastolic blood pressure greater than or equal to 90 mm Hg. A billion people affected globally and millions of them deaths annually. It is significant risk factor for cardiovascular disorders. Some medicinal plants are traditionally used for treatments hypertension. Psidium guava is one popular medicinal plant which is widely used in traditional medicine treatment of different diseases such as diabetes, vomiting, diarrhea and dyslipidemia. The study was designed to identify the effect of P. guava leaf extract on hypertension in guinea pigs. The study was conducted on eight male guinea pigs to measure the effect of ethanol P. guava leaf extract by using invasive methods. The result was analyzed by using independent student t test and one way ANOVA. Ethanol extract of P. guava leaf showed a significant (p=0.05, p=0.001) reduction of blood pressure of in normotensive guinea pigs in dose dependent manner. The effect of P. guava leaf extract in reduction of blood pressure is may be due to a number of phytochemical contents. VL - 5 IS - 3 ER -
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