Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children

Esra Akyuz Ozkan; Hashem E. Khosroshahi; Halil Ibrahim Serin; Zeynep Tuba Ozdemir; Mahmut Kilic; U. Aliye Gecit; Meral Ekim

doi:doi:10.11648/j.ajhr.20150303.25

Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children

Esra Akyuz Ozkan, Hashem E. Khosroshahi, Halil Ibrahim Serin, Zeynep Tuba Ozdemir, Mahmut Kilic, U. Aliye Gecit, Meral Ekim

Published in American Journal of Health Research (Volume 3, Issue 3)

Received: 11 May 2015 Accepted: 15 May 2015 Published: 26 May 2015

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Abstract

Background: Obesity has a risk factor for sudden cardiac death, because of the tendency to develop arrhythmias. Delay in cardiac repolarization is reflected as QTc prolongation on electrocardiogram. The aim of this study was to investigate QTc interval in obese children and assess the relation between cardiac risk factors and QTc interval. Materials and Methods: Forty five obese children whose body mass index (BMI) persentil was > % 95th and eighty seven control group were enrolled in this study. QTc was derived using Bazett’s Formula. Results: Mean QTc value was found significantly longer in obese children (413.89±23.27ms) than control group (398.95±24.28ms) (p= 0,001) and also prolonged QTc frequency was more than six times in obese (% 15.6) than control group (%2.4). BMI, systolic and diastolic BP, total cholesterol, triglyceride, low-density lipoprotein (LDL), fasting glucose, insulin, left ventricular mass (LVM) and carotid intima media thickness (CIMT) were significantly higher and high-density lipoprotein (HDL) levels and HOMA-IR values were lower in obese group compared with the controls. There was no correlation between QTc, metabolic parameters, systolic and diastolic BP, BMI, LVM and CIMT in obese group. Conclusion: QTc prolongation can be seen more common in obese children and may result in sudden death. So obese children must be followed closely regarding QTc interval.

Published in	American Journal of Health Research (Volume 3, Issue 3)
DOI	10.11648/j.ajhr.20150303.25
Page(s)	194-197
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Cardiovascular Risk Factors, Carotid Intima-Media Thickness, Children, Obesity, QTc Interval

References

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Esra Akyuz Ozkan, Hashem E. Khosroshahi, Halil Ibrahim Serin, Zeynep Tuba Ozdemir, Mahmut Kilic, et al. (2015). Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children. American Journal of Health Research, 3(3), 194-197. https://doi.org/10.11648/j.ajhr.20150303.25

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ACS Style

Esra Akyuz Ozkan; Hashem E. Khosroshahi; Halil Ibrahim Serin; Zeynep Tuba Ozdemir; Mahmut Kilic, et al. Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children. Am. J. Health Res. 2015, 3(3), 194-197. doi: 10.11648/j.ajhr.20150303.25

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AMA Style

Esra Akyuz Ozkan, Hashem E. Khosroshahi, Halil Ibrahim Serin, Zeynep Tuba Ozdemir, Mahmut Kilic, et al. Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children. Am J Health Res. 2015;3(3):194-197. doi: 10.11648/j.ajhr.20150303.25

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@article{10.11648/j.ajhr.20150303.25,
  author = {Esra Akyuz Ozkan and Hashem E. Khosroshahi and Halil Ibrahim Serin and Zeynep Tuba Ozdemir and Mahmut Kilic and U. Aliye Gecit and Meral Ekim},
  title = {Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children},
  journal = {American Journal of Health Research},
  volume = {3},
  number = {3},
  pages = {194-197},
  doi = {10.11648/j.ajhr.20150303.25},
  url = {https://doi.org/10.11648/j.ajhr.20150303.25},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20150303.25},
  abstract = {Background: Obesity has a risk factor for sudden cardiac death, because of the tendency to develop arrhythmias. Delay in cardiac repolarization is reflected as QTc prolongation on electrocardiogram. The aim of this study was to investigate QTc interval in obese children and assess the relation between cardiac risk factors and QTc interval. Materials and Methods: Forty five obese children whose body mass index (BMI) persentil was > % 95th and eighty seven control group were enrolled in this study. QTc was derived using Bazett’s Formula. Results: Mean QTc value was found significantly longer in obese children (413.89±23.27ms) than control group (398.95±24.28ms) (p= 0,001) and also prolonged QTc frequency was more than six times in obese (% 15.6) than control group (%2.4). BMI, systolic and diastolic BP, total cholesterol, triglyceride, low-density lipoprotein (LDL), fasting glucose, insulin, left ventricular mass (LVM) and carotid intima media thickness (CIMT) were significantly higher and high-density lipoprotein (HDL) levels and HOMA-IR values were lower in obese group compared with the controls. There was no correlation between QTc, metabolic parameters, systolic and diastolic BP, BMI, LVM and CIMT in obese group. Conclusion: QTc prolongation can be seen more common in obese children and may result in sudden death. So obese children must be followed closely regarding QTc interval.},
 year = {2015}
}

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TY - JOUR
T1 - Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children
AU - Esra Akyuz Ozkan
AU - Hashem E. Khosroshahi
AU - Halil Ibrahim Serin
AU - Zeynep Tuba Ozdemir
AU - Mahmut Kilic
AU - U. Aliye Gecit
AU - Meral Ekim
Y1 - 2015/05/26
PY - 2015
N1 - https://doi.org/10.11648/j.ajhr.20150303.25
DO - 10.11648/j.ajhr.20150303.25
T2 - American Journal of Health Research
JF - American Journal of Health Research
JO - American Journal of Health Research
SP - 194
EP - 197
PB - Science Publishing Group
SN - 2330-8796
UR - https://doi.org/10.11648/j.ajhr.20150303.25
AB - Background: Obesity has a risk factor for sudden cardiac death, because of the tendency to develop arrhythmias. Delay in cardiac repolarization is reflected as QTc prolongation on electrocardiogram. The aim of this study was to investigate QTc interval in obese children and assess the relation between cardiac risk factors and QTc interval. Materials and Methods: Forty five obese children whose body mass index (BMI) persentil was > % 95th and eighty seven control group were enrolled in this study. QTc was derived using Bazett’s Formula. Results: Mean QTc value was found significantly longer in obese children (413.89±23.27ms) than control group (398.95±24.28ms) (p= 0,001) and also prolonged QTc frequency was more than six times in obese (% 15.6) than control group (%2.4). BMI, systolic and diastolic BP, total cholesterol, triglyceride, low-density lipoprotein (LDL), fasting glucose, insulin, left ventricular mass (LVM) and carotid intima media thickness (CIMT) were significantly higher and high-density lipoprotein (HDL) levels and HOMA-IR values were lower in obese group compared with the controls. There was no correlation between QTc, metabolic parameters, systolic and diastolic BP, BMI, LVM and CIMT in obese group. Conclusion: QTc prolongation can be seen more common in obese children and may result in sudden death. So obese children must be followed closely regarding QTc interval.
VL - 3
IS - 3
ER -

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Author Information

Esra Akyuz Ozkan

Department of Pediatrics, Bozok University Medical Faculty, Yozgat, Turkey
Hashem E. Khosroshahi

Department of Pediatric Cardiology, Bozok University Medical Faculty, Yozgat, Turkey
Halil Ibrahim Serin

Department of Radiology, Bozok University Medical Faculty, Yozgat, Turkey
Zeynep Tuba Ozdemir

Department of Internal Medicine, Bozok University Medical Faculty, Yozgat, Turkey
Mahmut Kilic

Department of Public Health, Bozok University Medical Faculty, Yozgat, Turkey
U. Aliye Gecit

Department of Pediatrics, Bozok University Medical Faculty, Yozgat, Turkey
Meral Ekim

Department of Biochemistry, Bozok University Medical Faculty, Yozgat, Turkey

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APA Style

Esra Akyuz Ozkan, Hashem E. Khosroshahi, Halil Ibrahim Serin, Zeynep Tuba Ozdemir, Mahmut Kilic, et al. (2015). Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children. American Journal of Health Research, 3(3), 194-197. https://doi.org/10.11648/j.ajhr.20150303.25

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Esra Akyuz Ozkan; Hashem E. Khosroshahi; Halil Ibrahim Serin; Zeynep Tuba Ozdemir; Mahmut Kilic, et al. Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children. Am. J. Health Res. 2015, 3(3), 194-197. doi: 10.11648/j.ajhr.20150303.25

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AMA Style

Esra Akyuz Ozkan, Hashem E. Khosroshahi, Halil Ibrahim Serin, Zeynep Tuba Ozdemir, Mahmut Kilic, et al. Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children. Am J Health Res. 2015;3(3):194-197. doi: 10.11648/j.ajhr.20150303.25

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@article{10.11648/j.ajhr.20150303.25,
  author = {Esra Akyuz Ozkan and Hashem E. Khosroshahi and Halil Ibrahim Serin and Zeynep Tuba Ozdemir and Mahmut Kilic and U. Aliye Gecit and Meral Ekim},
  title = {Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children},
  journal = {American Journal of Health Research},
  volume = {3},
  number = {3},
  pages = {194-197},
  doi = {10.11648/j.ajhr.20150303.25},
  url = {https://doi.org/10.11648/j.ajhr.20150303.25},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20150303.25},
  abstract = {Background: Obesity has a risk factor for sudden cardiac death, because of the tendency to develop arrhythmias. Delay in cardiac repolarization is reflected as QTc prolongation on electrocardiogram. The aim of this study was to investigate QTc interval in obese children and assess the relation between cardiac risk factors and QTc interval. Materials and Methods: Forty five obese children whose body mass index (BMI) persentil was > % 95th and eighty seven control group were enrolled in this study. QTc was derived using Bazett’s Formula. Results: Mean QTc value was found significantly longer in obese children (413.89±23.27ms) than control group (398.95±24.28ms) (p= 0,001) and also prolonged QTc frequency was more than six times in obese (% 15.6) than control group (%2.4). BMI, systolic and diastolic BP, total cholesterol, triglyceride, low-density lipoprotein (LDL), fasting glucose, insulin, left ventricular mass (LVM) and carotid intima media thickness (CIMT) were significantly higher and high-density lipoprotein (HDL) levels and HOMA-IR values were lower in obese group compared with the controls. There was no correlation between QTc, metabolic parameters, systolic and diastolic BP, BMI, LVM and CIMT in obese group. Conclusion: QTc prolongation can be seen more common in obese children and may result in sudden death. So obese children must be followed closely regarding QTc interval.},
 year = {2015}
}

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