Within decade years, the deuterium dilution techniques are largely used in developing countries for breast milk output and body composition which are the important indicators of public health nutrition interventions. But the implementation of these techniques needs a familiarity with standard operating procedures. This paper presented the challenge met while using these stable isotope methods among Beninese children. The checking data and estimate of deuterium equilibration period were tested on 15 children aged 6-22 months for the body composition (BC) and 08 mother-child pairs having 5.5 months children aged for assessing breast milk intake (BMI). We have found that collecting saliva from 6 months children was very demanding. Children above 6 months aged chewed up the dentals swabs or cotton wool. Instead of cotton stalk, mother’s index finger has been used to overcome saliva collection challenge. For BC measurement, some mothers got angry and left before the third saliva collection. Seven children have rejected the dose or vomited immediately after the dose administration. The plateau equilibration was between 2 and 3 hours. Concerning data quality, the Total Body Water percentage at 2, 2.5 and 3 hours were between 40-75% for 7 children. Only one over 8 children was less than 60mg/kg of total error for BMI output. These results are crucial to conduct the large study. It showed precautions that might be taken into account in order assure high quality data about BMI output and children BC and therefore to improve the quality of the assessment public health actions.
| Published in | World Journal of Public Health (Volume 4, Issue 2) |
| DOI | 10.11648/j.wjph.20190402.12 |
| Page(s) | 34-42 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Deuterium Oxide, Fat Free Mass, Fat Mass, Breastmilk
| [1] | International Food Policy Research Institute (2016). Global Nutrition Report 2016: From Promise to Impact: Ending Malnutrition by 2030. Washington, DC. |
| [2] | International Atomic Energy Agency (2014). IAEA Bulletin 55-1-March 2014. http://www.iaea.org/bulletin (accessed July 2016). |
| [3] | International Atomic Energy Agency (2017). Infant and young child nutrition. https://www.iaea.org/topics/infant-and-young-child-nutrition. (accessed June 2018) |
| [4] | Owino O. V., Slater C., Loechl U. C. (2017). Using stable isotope techniques in nutrition assessments and tracking of global targets post-2015. Conference on ‘Nutrition dynamics in Africa: Opportunities and challenges for meeting the sustainable development goals. Proceedings of the Nutrition Society: 1-9. |
| [5] | International Atomic Energy Agency (2017). Contributing to the evidence base to improve Stunting reduction programmes. https://www.iaea.org/projects/tc/int6058. (accessed June 2017) |
| [6] | International Atomic Energy Agency (2016). IAEA recommends technique to improve Nutrition assessment in Africa. https://www.iaea.org/newscenter/news/iaea-recommends-nuclear-techniques-to-improve-nutrition-assessments-in-africa (accessed Sept 2018). |
| [7] | International Atomic Energy Agency (2010). Stable Isotope Technique to Assess Intake of Human Milk in Breastfed Infants. IAEA Human Health Series No. 7. Vienna: IAEA. http://www-pub.iaea.org/MTCD/Publications/PDF/Pub1429 web.pdf (accessed July 2016) |
| [8] | International Atomic Energy Agency (2009). Assessment of Body Composition and Total Energy Expenditure in Humans Using Stable Isotope Techniques. IAEA Human Health Series No. 3 Vienna. https://nucleus.iaea.org/HHW/Nutrition/ TotalEnergyExpenditure/index.html (accessed July 2016) |
| [9] | Fabiansen C, Yaméogo CW, Devi S, Friis H, Kurpad A, et al. (2017). Deuterium dilution technique for body composition assessment: resolving methodological issues in children with moderate acute malnutrition. Isotopes in Environmental and Health Studies. |
| [10] | Fomon SJ, Haschke F, Ziegler EE, al e (1982). Body composition of reference children from birth to age 10 years. Am J Clin Nutr 35: 1169-1175. |
| [11] | Lohman TG (1992). Estimating body composition in children and the elderly; Advances in body composition assessment. Human Kinetics. |
| [12] | Racette SB, Schoeller DA, Luke AH, et al (1994). Relative dilution spaces of 2H- and 18O-labeled water in humans. Am J Physiol-Endocrinal Metab 267: E585-E590. |
| [13] | Wells JCK, Ritz P, Davies PSW, al; e (1998). Factors affecting the 2H to 18O dilution space ratio in infants. Pediatr Res 43: 467-471. |
| [14] | Wong WW, Cochran WJ, Klish WJ, et al (1988). In vivo isotope fractionation factors and the measurement of deuterium and oxygen-18 dilution spaces from plasma, urine, saliva, respiratory water vaporand carbon dioxide. Am J Clin Nutr 47: 1-6. |
| [15] | Slater Christine (2014). Guidance notes on evaluation of data in the Excel spreadsheet to calculate human milk intake by breastfed infants. https://humanhealth.iaea.org/HHW/ Nutrition/MilkIntake/index.html. (Accessed July 2018). |
| [16] | Slater Christine (2013). Instructions for assessing body composition in infants and young children using the deuterium dilution technique: CRP E4.30.28 Standard operating procedure for assessment of body composition in infants and young children using the deuterium dilution technique: Saliva sampling and dose administration. https://humanhealthiaeaorg/ HHW/Nutrition/MilkIntake/indexhtml (Accessed July 2018). |
| [17] | Traver M. A. L., Martinez F. E., Ferriolli E., et al (2009). Deuterium Equilibrium Time in Saliva of Newborn Infants. J Pediatr Gastroenterol Nutr 48: 471-474. |
APA Style
Jaurès Hontongnon Felix Lokonon, Waliou Bodounrin Ayanda Amoussa Hounkpatin, Adama Diouf, Aubierge Joelle Flenon, Félix Bodjrenou Sonon, et al. (2019). A Trial Implementation of Using Deuterium Oxide Dose-to-Mother and Dilution Technique Among Beninese Children: Challenge and Critical Points. World Journal of Public Health, 4(2), 34-42. https://doi.org/10.11648/j.wjph.20190402.12
ACS Style
Jaurès Hontongnon Felix Lokonon; Waliou Bodounrin Ayanda Amoussa Hounkpatin; Adama Diouf; Aubierge Joelle Flenon; Félix Bodjrenou Sonon, et al. A Trial Implementation of Using Deuterium Oxide Dose-to-Mother and Dilution Technique Among Beninese Children: Challenge and Critical Points. World J. Public Health 2019, 4(2), 34-42. doi: 10.11648/j.wjph.20190402.12
AMA Style
Jaurès Hontongnon Felix Lokonon, Waliou Bodounrin Ayanda Amoussa Hounkpatin, Adama Diouf, Aubierge Joelle Flenon, Félix Bodjrenou Sonon, et al. A Trial Implementation of Using Deuterium Oxide Dose-to-Mother and Dilution Technique Among Beninese Children: Challenge and Critical Points. World J Public Health. 2019;4(2):34-42. doi: 10.11648/j.wjph.20190402.12
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.wjph.20190402.12,
author = {Jaurès Hontongnon Felix Lokonon and Waliou Bodounrin Ayanda Amoussa Hounkpatin and Adama Diouf and Aubierge Joelle Flenon and Félix Bodjrenou Sonon and Polycarpe Pierre Adechola Kayodé and Nicole Idohou Dossou},
title = {A Trial Implementation of Using Deuterium Oxide Dose-to-Mother and Dilution Technique Among Beninese Children: Challenge and Critical Points},
journal = {World Journal of Public Health},
volume = {4},
number = {2},
pages = {34-42},
doi = {10.11648/j.wjph.20190402.12},
url = {https://doi.org/10.11648/j.wjph.20190402.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20190402.12},
abstract = {Within decade years, the deuterium dilution techniques are largely used in developing countries for breast milk output and body composition which are the important indicators of public health nutrition interventions. But the implementation of these techniques needs a familiarity with standard operating procedures. This paper presented the challenge met while using these stable isotope methods among Beninese children. The checking data and estimate of deuterium equilibration period were tested on 15 children aged 6-22 months for the body composition (BC) and 08 mother-child pairs having 5.5 months children aged for assessing breast milk intake (BMI). We have found that collecting saliva from 6 months children was very demanding. Children above 6 months aged chewed up the dentals swabs or cotton wool. Instead of cotton stalk, mother’s index finger has been used to overcome saliva collection challenge. For BC measurement, some mothers got angry and left before the third saliva collection. Seven children have rejected the dose or vomited immediately after the dose administration. The plateau equilibration was between 2 and 3 hours. Concerning data quality, the Total Body Water percentage at 2, 2.5 and 3 hours were between 40-75% for 7 children. Only one over 8 children was less than 60mg/kg of total error for BMI output. These results are crucial to conduct the large study. It showed precautions that might be taken into account in order assure high quality data about BMI output and children BC and therefore to improve the quality of the assessment public health actions.},
year = {2019}
}
TY - JOUR T1 - A Trial Implementation of Using Deuterium Oxide Dose-to-Mother and Dilution Technique Among Beninese Children: Challenge and Critical Points AU - Jaurès Hontongnon Felix Lokonon AU - Waliou Bodounrin Ayanda Amoussa Hounkpatin AU - Adama Diouf AU - Aubierge Joelle Flenon AU - Félix Bodjrenou Sonon AU - Polycarpe Pierre Adechola Kayodé AU - Nicole Idohou Dossou Y1 - 2019/06/12 PY - 2019 N1 - https://doi.org/10.11648/j.wjph.20190402.12 DO - 10.11648/j.wjph.20190402.12 T2 - World Journal of Public Health JF - World Journal of Public Health JO - World Journal of Public Health SP - 34 EP - 42 PB - Science Publishing Group SN - 2637-6059 UR - https://doi.org/10.11648/j.wjph.20190402.12 AB - Within decade years, the deuterium dilution techniques are largely used in developing countries for breast milk output and body composition which are the important indicators of public health nutrition interventions. But the implementation of these techniques needs a familiarity with standard operating procedures. This paper presented the challenge met while using these stable isotope methods among Beninese children. The checking data and estimate of deuterium equilibration period were tested on 15 children aged 6-22 months for the body composition (BC) and 08 mother-child pairs having 5.5 months children aged for assessing breast milk intake (BMI). We have found that collecting saliva from 6 months children was very demanding. Children above 6 months aged chewed up the dentals swabs or cotton wool. Instead of cotton stalk, mother’s index finger has been used to overcome saliva collection challenge. For BC measurement, some mothers got angry and left before the third saliva collection. Seven children have rejected the dose or vomited immediately after the dose administration. The plateau equilibration was between 2 and 3 hours. Concerning data quality, the Total Body Water percentage at 2, 2.5 and 3 hours were between 40-75% for 7 children. Only one over 8 children was less than 60mg/kg of total error for BMI output. These results are crucial to conduct the large study. It showed precautions that might be taken into account in order assure high quality data about BMI output and children BC and therefore to improve the quality of the assessment public health actions. VL - 4 IS - 2 ER -
Email: